Research
Exploring the intersection of computation, biology, and medicine — with a focus on neurodegenerative diseases and precision healthcare.
ALS & Neurodegenerative Diseases
Investigating the molecular mechanisms of Amyotrophic Lateral Sclerosis and related neurodegenerative conditions through data-driven approaches.
Computational Biology
Using computational methods to analyze biological data, from genomic sequences to protein structures, to understand the mechanisms of disease.
Precision Medicine
Developing approaches for tailored treatment strategies using multi-omics data integration, biomarker discovery, and patient stratification.
AI for Healthcare
Applying machine learning and deep learning to clinical data, medical imaging, and drug discovery to accelerate healthcare innovation.
Selected Publications
My published papers, preprints, and research contributions.
In silico Discovery of Small-Molecule Modulators of Differentially Expressed Genes Associated with Reduced Ataxin-2 Levels in an RTN4R Knockdown Model of Amyotrophic Lateral Sclerosis
Fatoki T.H., Akereja A.K., Akinyelu J., Balogun T.C., Ogunleye S.O., Oyebiyi O.R., Akerele B.O., and Jamiyu A. Saliu J.A.
Development of OTPD4ALS: A Specialized Database for Efficient Screening of Anti-Amyotrophic Lateral Sclerosis Drug Candidates
Ogunleye S.O., Adeyeye T.O., Aderibigbe I.E., Fatoki T.H.
In Silico Investigation of Lipid-Based Compounds Implicated in Amyotrophic Lateral Sclerosis
Fatoki T.H., Saliu I.O., Balogun C.T., Oyebiyi R.O., Ogunleye S.O., et al.
Driving Questions
The questions that guide my research curiosity and learning.
How can machine learning and multi-omics data be combined to improve our understanding of ALS and other neurodegenerative diseases?
Can AI-driven approaches uncover biomarkers that enable earlier diagnosis and more personalized treatment strategies?
How can interpretable machine learning models support clinical decision-making while maintaining trust and transparency?
What insights can large biological and protein foundation models provide for drug discovery and target identification?
How can computational methods accelerate the translation of biological data into actionable healthcare outcomes?
Reading List
Key books, papers, and reviews shaping my understanding.
Deep Learning for the Life Sciences
Bharath Ramsundar et al.
The Psychology of Money
Morgan Housel
Atomic Habits
James Clear
Attention Is All You Need
Vaswani et al.
Highly accurate protein structure prediction with AlphaFold
Jumper et al.